Research Studies

The Eynsham Medical Group takes part in a number of research studies conducted by the University of Oxford looking for ways to improve patient treatment. If you would like to take part in any of these studies or find out more about them please book a telephone consultation with our research nurse, Janice Williams.

We are currently taking part in the following studies:

Toast Study

What are we hoping to find out?

Does using a single dose of oral steroid medication will reduce the length and severity of people suffering from an acute sore throat?

Who is suitable?

Anyone aged 18 years and over who presents to their GP with a sore throat and painful swallowing which has been of less than 1 week duration.

What does it involve?

Some screening questions from the GP or research nurse at your GP practice followed by a throat swab and single capsule of medication. The medication may be a steroid medicine or placebo.

BARACK-D study

What are we hoping to find out?

Whether people with moderate level kidney impairment benefit from a medication called spironolactone taken over a 3 year period

Who is suitable?

Anyone aged 18 years and over with a moderate level of Chronic Kidney Disease defined by results from 2 blood tests in the last year.

What does it involve?

Seeing a GP/research nurse at the surgery and completing baseline blood tests and blood pressure along with a few questions. Follow up over the next 3 years with visits to the research nurse for further blood test and blood pressure monitoring.

OASC Study

What are we hoping to find out?

Whether using a course of oral steroid medication will reduce the length and severity of people suffering from an acute chest infection.

Who is suitable?

Anyone aged 18 years and over who presents to their GP with chest infection symptoms of less than 1 month’s duration.

What does it involve?

Some screening questions from the GP or research nurse at your GP  practice, following which your doctor will randomise you via the research trial computer to receive a 5 day course of oral steroid or a 5 day course of placebo medication [both doctor and patient aren’t aware of what they receive]. You will need to complete a daily diary.

Completed Studies

The Montelukast for Post-Infectious Cough in Adults (MAC) Trial

We are delighted to let you know that the findings of the MAC trial have been published online in The Lancet Respiratory Medicine:

http://www.thelancet.com/journals/lanres/article/PIIS2213-2600%2813%2970245-5/abstract

276 patients were recruited into this trial, of whom 70 (25%) had whooping cough. Montelukast is not an effective treatment for post-infectious persistent cough; however, the good news is that in around half of patients the cough will almost completely settle two weeks after initial presentation in primary care. Thank you to everyone who took part in this study.

Effect of Oral Prednisolone on Symptom Duration and Severity in Nonasthmatic Adults With Acute Lower Respiratory Tract Infection 
A Randomized Clinical Trial

View information on the clinical trial

Other Completed Studies

The following studies have now finished recruiting patients: CAPS (The Children and Persistent Cough Study), AIRS (A Study of Auto inflation for schoolchildren with glue ear). Thank you to everyone who took part. The results of the trial are available at http://www.phc.ox.ac.uk/

Useful links

Join Dementia Research
A new service which allows people to register their interest in participating in dementia research and be matched to suitable studies.